R-171. Oocyte morphology and cytogenetic disorders

Cytogenetic effects of caffeine during in vivo mouse oocyte maturation.

Numerous investigators have studied the reproductive and genetic toxicity of caffeine. Caffeine has also been reported to retard meiotic progression and induce aneuploidy in hamster oocytes in vitro. However, the ability of caffeine to induce aneuploidy in mammalian oocytes in vivo has not been reported. The objective of this study was to test the hypothesis that chemical-induced perturbations ...

P-25: Role of Oocyte Morphology on ARTOutcome

Background: The cause of fertilization failure in IVF is most often due to the absence of sperm penetration but the reason why fertilization does not occur when intracytoplasmic sperm injection (ICSI) is applied is not clear. However some intrinsic oocyte problems may also be responsible for fertilization failure. It has been reported that 13% of unfertilized oocytes after IVF show morphologica...

Morphology of Blood Disorders Morphology of Blood Disorders Second Edition

Cytogenetic Techniques in Diagnosing Genetic Disorders

When the discovery of giant banded, salivary chromosomes in Drosophila was made by Painter in 1934, it gave a tremendous impact to the cytological work carried out in Drosophila. This made it possible to identify the chromosomes individually and also to discern the specific segments of the chromosome. Followed by this, cytogenetics bloomed with the establishment of chromosome number in man as 4...

Classical and Molecular Cytogenetic Analysis of Hematolymphoid Disorders